Wednesday, March 27, 2019

Strychnine :: Botany

StrychnineStrychnine is a toxic alkaloid, C21H22N2O2, obtained in colorless or white rhombic crystals. These contrive a bitter taste and melt at around 290( C (4 p.1). Alkaloids atomic number 18 any class of naturally occurring organic nitrogen containing bases, usually containing unmatchable or more of these nitrogen atoms in a ring of atoms called a cyclic system. Alkaloids are primarily found in plants and are predominant in flowering plant species. The function of alkaloids in plants is thought to be simply a waste product of the plants metabolic processes, but reliable research may suggest a specific biological function. This is observable in some plants as the levels of alkaloid increase just prior to ejaculate formation and then drops off after the seed is ripe. This evidence suggests doable mechanisms of maturation and possible defense, against certain insect species (5 p.2). Strychnine, being an alkaloid, is slightly fat-soluble in water, but is more soluble in alco hol and is released from its salts by alkalis. Many of the commercial alkaloids are found in the genus Strychnos. Strychnine was the first alkaloid to be identified in plants of the genus Strychnos, Family Loganiaceae. Strychnos, created by Linnaeus in 1753, is a genus of trees and rise shrubs of the gentian order. From the rack of biological diversity, it is the most important genus of the Loganiaceae family (6 p.1). The genus contains 196 various species and is distributed throughout the torrid regions of Asia (58 species), America (64) and Africa (75). The Strychnos alkaloids were originally classified based solely on their geographic origin. Asian Strychnos was thought to contain strychnine and the American Strychnos were thought to contain curarizing ammonium salts (6 p.2). Plants of the genus Strychnos have opposite leaves and bear cymes of white or yellowish flowers that have a four-lobed or five-lobed calyx, a four-parted or five-parted corolla, five stamens, a recluse p istil and bears fruit in the form of a berry. The seeds and bark of many plants in this genus contain the powerful poison (4 p.2). Strychnine is obtained commercially from the seeds of the Saint-ignatiuss-bean and from the nux-vomica tree. Strychnine was first discovered by French chemist Joseph-Bienaime Caenoiu and Pierre-Joseph Pelletier in 1818 in the Saint-Ignatins-bean (S. ignatii)(1 p.2). Strychnos ignatii is a woody climbing shrub of the Philippines. It was introduced into Cochin China and is highly esteemed there as a medicine. It got its name from the attention it attracted from the Jesuits.

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